Peptide Database

Peptide NameBovine beta-defensin 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC109H193N35O31S5

DescriptionStandard

        SCVRNKGICVPIRCPGSMKQIGTCV
    

Molecular Weight2650.24 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)3.42

Net Charge (pH 7.4) 3.15

Charge Density (pH 7.0) 0.1367

GRAVY Index0.30

Hydrophobic Moment 0.47

Boman Index0.03

Instability Index42.68

Aliphatic Index 81.60

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1066.85

LogP -13.19

H-bond Donors 41.0

H-bond Acceptors 40.0

Rotatable Bonds 87.0

Heavy Atoms 180.0

Ring Count 2.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0135276 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)