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MYP_074206
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Basic Information
MAP-04-04
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
11 amino acids
C75H126N32O12
Standard
Sequence
KRLRRVWRRWR
Physicochemical Analysis
1668.01 Da
12.00
6.76
6.55
0.6145
-2.25
0.97
-1.17
212.45
61.82
0.1818
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
783.32
-4.89
33.0
19.0
56.0
119.0
4.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0005497 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ixosin-derived peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Cytotoxic
MCF-7
75 μM
Cell viability assay
PMID23993331 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23993331/
RECORD: Rec_0006483 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PMID22578463 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22578463/
RECORD: Rec_0013985 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeroginosa
20 μM
MIC
PMID22578463 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22578463/
RECORD: Rec_0034010 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
100 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/22578463/ PMID22578463 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22578463/
RECORD: Rec_0057689 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeroginosa
20 μM
MIC90
PMID22578463 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22578463/
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