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MYP_074186
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Basic Information
Esculentin-1ISa (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
46 amino acids
C214H367N59O59S3
Standard
Sequence
GIFSKFAGKGIKNLLVKGVKNIGKEVGMDVIRTGIDIAGCKIKGEC
Physicochemical Analysis
4806.76 Da
9.63
4.74
4.49
0.1030
0.22
0.73
0.12
2.00
105.87
0.0435
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1918.72
-16.83
68.0
67.0
174.0
335.0
2.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0229200 VERIFIED: YES
Provenance & Taxonomy
Odorrana ishikawae [Animal]
Esculentin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
40-46
Bio-Activity Profile
Antimicrobial
Bacillus subtilis
25 μM
MIC
PaperIdentification and characterization of antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae
RECORD: Rec_0241204 VERIFIED: YES
Provenance & Taxonomy
Odorrana ishikawae [Animal]
Esculentin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis ATCC 6633
25 μM
MIC
PMID21193000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21193000/
RECORD: Rec_0265008 VERIFIED: YES
Provenance & Taxonomy
Odorrana ishikawae [Animal]
Esculentin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
40-46
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli (MC=6.3 μM)
PMID21193000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21193000/
RECORD: Rec_0343909 VERIFIED: YES
Provenance & Taxonomy
Odorrana ishikawae [Animal]
Esculentin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
40-46
Bio-Activity Profile
Antimicrobial
Candida albicans
>100 μM
MIC
PaperIdentification and characterization of antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae
RECORD: Rec_0361229 VERIFIED: YES
Provenance & Taxonomy
Odorrana ishikawae [Animal]
Esculentin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
40-46
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus (MRSA)
25 μM
MIC
PMID21193000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21193000/
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