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MYP_074167
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Basic Information
RL4 (homologue of Pc-CATH1)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
22 amino acids
C127H201N33O27
Standard
Sequence
FWPVVIRTVVAGYNLYRAIKKK
Physicochemical Analysis
2622.16 Da
10.56
4.76
4.54
0.2161
0.25
0.70
0.10
2.90
115.00
0.1818
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
987.06
-3.45
36.0
32.0
83.0
187.0
6.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0111395 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
1.172 μg/mL
MIC
PaperPMCID: PMC4131589 PMID4131589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/4131589/
RECORD: Rec_0122635 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
200 μg/mL
Hemolysis
PaperPMCID: PMC4131589 PMID4131589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/4131589/
RECORD: Rec_0231687 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
28.125 μg/mL
MIC
PaperPMCID: PMC4131589 PMID4131589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/4131589/
RECORD: Rec_0314075 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
0.879 μg/mL
MIC
PaperPMCID: PMC4131589 PMID4131589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/4131589/
RECORD: Rec_0337698 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP04154
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