Peptide Database

Peptide NameHepcidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length85 amino acids

Chemical FormulaC400H654N120O117S12

DescriptionStandard

        MKLLCIAAVTLCVCVLLSAAVPFSQTLTQETGRGDTRNEERWTPAAAEETHPLALLRTKRQSHLSLCRYCCGCCKNKGCGYCCRF
    

Molecular Weight9400.99 Da

Isoelectric Point (pI)8.71

Net Charge (pH 7.0)4.57

Net Charge (pH 7.4) 4.08

Charge Density (pH 7.0) 0.0538

GRAVY Index0.02

Hydrophobic Moment 0.53

Boman Index-0.02

Instability Index39.98

Aliphatic Index 78.12

Aromaticity 0.0588

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 9105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3814.35

LogP -42.13

H-bond Donors 147.0

H-bond Acceptors 136.0

Rotatable Bonds 308.0

Heavy Atoms 649.0

Ring Count 11.0

Amide Bonds 89.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0035689 VERIFIED: NO

Provenance & Taxonomy

OrganismParamormyrops kingsleyae [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal