Peptide Database

Peptide NameRibonuclease pancreatic (1-48)[C26,40S]

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length48 amino acids

Chemical FormulaC231H377N81O76S4

DescriptionStandard

        KESRAKKFQRQHMDSDSSPSSSSTYSNQMMRRRNMTQGRSKPVNTFVH
    

Molecular Weight5633.22 Da

Isoelectric Point (pI)11.40

Net Charge (pH 7.0)6.93

Net Charge (pH 7.4) 6.62

Charge Density (pH 7.0) 0.1445

GRAVY Index-1.57

Hydrophobic Moment 0.52

Boman Index-0.49

Instability Index91.99

Aliphatic Index 14.17

Aromaticity 0.0625

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2643.03

LogP -39.80

H-bond Donors 95.0

H-bond Acceptors 89.0

Rotatable Bonds 195.0

Heavy Atoms 392.0

Ring Count 7.0

Amide Bonds 54.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0015559 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic

RECORD: Rec_0082590 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBrevinin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCandida albicans ATCC 90028

RECORD: Rec_0203966 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

RECORD: Rec_0337179 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBrevinin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCandida albicans ATCC 90028 (MFC100 = 3.75 ± 0.50 microM (Sabouraud Broth)), C. albicans ATCC 90028 (MFC100 = 3.75 ± 0.30 microM (PBS)), (IC50 = 2.10 ±0.20 microM)

Activity2.10 ±0.20 μM

MethodIC50

RECORD: Rec_0369518 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetNot available