Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length477 amino acids

Chemical FormulaC2366H3737N595O687S15

DescriptionStandard

        MFLWFVLVLVNLVSVATGTNAGVKVRLTQKGLEYGRQIGIASIQQKLRTIKVPDISGTETVDPIGKVQYSFTGMQIVNLGLPKSALGLVPDTGVMLSIGNGYINLHGNWRVKYLRIIKDSGSFDLAVSELTISTTIAVTNDDTGHPTVSMTNCAATVGSVNVKFHGGASWLYNLFSSFINKALCNALQKQVRNLGCDCPLYHPLDVFTFNLSAVSDLPFDQYAEIEYSMVGSPVISNTSIDLGLKGEFYNIGQHKEPPFSPTPFSFLSQDTDIIYIGVSAFTINSAGFVYNRAGALRLYITDDMIPSGSPIRLNTKTFGTFIPQIEKMYPGLMMKLLVETVKEPLITFEPNNVTVQASSTVTAYAIQPNSTLSPLFVLNLEGSVSTHIYVTELKLAGNMTLNKIDISLAKSYVGPFQVTSLDNIFTIVLKVAVIPKVNAHLQEGYPLPAIGKMQLVNSRLQVLKDYLLIGTDVQFTG
    

Molecular Weight51990.53 Da

Isoelectric Point (pI)7.04

Net Charge (pH 7.0)0.09

Net Charge (pH 7.4) -0.64

Charge Density (pH 7.0) 0.0002

GRAVY Index0.22

Hydrophobic Moment 0.68

Boman Index0.20

Instability Index29.07

Aliphatic Index 104.76

Aromaticity 0.0922

Extinction Coeff. Reduced 43320.00

Extinction Coeff. Oxidized 43570.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0330483 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria