Peptide Database

Peptide NameM6

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC49H95N21O15

DescriptionStandard

        KRKSGSGSKRK
    

Molecular Weight1218.41 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.55

Charge Density (pH 7.0) 0.5233

GRAVY Index-2.53

Hydrophobic Moment 0.28

Boman Index-0.97

Instability Index68.36

Aliphatic Index 0.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 642.89

LogP -10.47

H-bond Donors 25.0

H-bond Acceptors 21.0

Rotatable Bonds 48.0

Heavy Atoms 85.0

Ring Count 0.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0385959 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCecropin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetHuman histiocytic lymphoma U-937

Activity64 μM

MethodLD50

RECORD: Rec_0397477 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Anticancer

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