Peptide Database

Peptide NamePyocin large subunit

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length452 amino acids

Chemical FormulaC2158H3381N583O647S16

DescriptionStandard

        MGYRPNIMGKGKALSCDKTTTGAKLIASLPTSQYMVYGHAVIRVGDSTTECPKCGKRGRVIEGEPSFIIMGKVLAVDGAIVLCGCPSGSNRIIAPFGQWLGAGLSPAQQSAEKQAAKIAADAAERAENKAKEQAKRSMPVFAKSQERGEGNTEAGTGPETHENFALMGYFRAVPLPEPEQHAQSAKRPASPPPEPEKPWYKKLFGGASSAAPAVAVPVAASTVFPSGSAALEWVGGRFITAGSWAVRAVVPFGEIAAAGAGAPIAVALIGMMPRTLNSGEQDFIDQMRLAQLAESGGKAPTRVRFRWEDDGHGSLSPKGYHTPTESGLSEVPVREMKLNTKTGLYEFTTEGVKPVTIYWNPDKLELDIPSNTGHQGSPSLPSSITVLPIPEKVGSDIESYPAPTEGDFEDYILIFLGTDMPPIYIYLSKPPVEFLEVELYSDFKRRSRQGKY
    

Molecular Weight48357.49 Da

Isoelectric Point (pI)6.64

Net Charge (pH 7.0)-0.95

Net Charge (pH 7.4) -1.68

Charge Density (pH 7.0) -0.0021

GRAVY Index-0.29

Hydrophobic Moment 0.63

Boman Index0.05

Instability Index51.98

Aliphatic Index 73.03

Aromaticity 0.0796

Extinction Coeff. Reduced 53860.00

Extinction Coeff. Oxidized 54110.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0038649 VERIFIED: YES

Provenance & Taxonomy

OrganismHafnia alvei [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)