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MYP_073989
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Basic Information
Maximin-Hu
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibiotic activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
20 amino acids
C90H157N23O26
Standard
Sequence
ILGPVLSLVGNALGGLLKNE
Physicochemical Analysis
1977.35 Da
6.22
-0.23
-0.44
-0.0116
0.95
0.48
0.43
22.20
170.50
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
777.16
-5.97
25.0
26.0
66.0
139.0
1.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0072613 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
Maximin
161274
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperR. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima PMID11835991 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11835991/
RECORD: Rec_0223358 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 50.0%, E 0.0%, T 25.0%, C 25.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0315508 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
161274
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperIsolation and structural characterisation of antimicrobial peptides from the venom of the Chinese large-webbed bell toad (Bombina maxima).
RECORD: Rec_0329792 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
Maximin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0333744 VERIFIED: NO
Provenance & Taxonomy
Bombina maxima [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Amphibian defense peptide Antibiotic Antimicrobial Non-hemolytic Non-ribosomal
Qualitative functional evidence
Evidence URLhttps://www.uniprot.org/uniprotkb/P83087/entry; https://bblserver.org.in/ampdb/
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