Peptide Database

Peptide NamePotassium channel toxin alpha-KTx 3.11

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC167H278N54O49S8

DescriptionStandard

        GVPTDVKCRGSPQCIQPCKDAGMRFGKCMNGKCHCTPK
    

Molecular Weight4082.85 Da

Isoelectric Point (pI)9.13

Net Charge (pH 7.0)4.79

Net Charge (pH 7.4) 4.44

Charge Density (pH 7.0) 0.1259

GRAVY Index-0.62

Hydrophobic Moment 0.58

Boman Index-0.17

Instability Index44.87

Aliphatic Index 28.16

Aromaticity 0.0263

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1652.00

LogP -21.53

H-bond Donors 61.0

H-bond Acceptors 63.0

Rotatable Bonds 134.0

Heavy Atoms 278.0

Ring Count 6.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0017409 VERIFIED: YES

Provenance & Taxonomy

OrganismOdontobuthus doriae [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-28; 14-33; 18-35

Bio-Activity Profile

Function

Toxin

Activity0.0072 μM

MethodIC50