Peptide Database

Peptide NameProgonadoliberin-2

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC315H500N94O95S2

DescriptionStandard

        QHWSHGWYPGGKRELDSFGTSEISEEIKLCEAGECSYLTPQRRSVLRNILLDALARELQKRK
    

Molecular Weight7188.04 Da

Isoelectric Point (pI)8.02

Net Charge (pH 7.0)0.93

Net Charge (pH 7.4) 0.58

Charge Density (pH 7.0) 0.0150

GRAVY Index-0.79

Hydrophobic Moment 0.71

Boman Index-0.18

Instability Index85.35

Aliphatic Index 78.71

Aromaticity 0.0806

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3095.62

LogP -30.77

H-bond Donors 112.0

H-bond Acceptors 100.0

Rotatable Bonds 244.0

Heavy Atoms 506.0

Ring Count 11.0

Amide Bonds 65.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0120877 VERIFIED: YES

Provenance & Taxonomy

OrganismSparus aurata [Animal]

FamilyProgonadoliberin

Tax ID8175

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour