Peptide Database

Peptide NameBovine Beta-defensin 11

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC115H201N37O32S5

DescriptionStandard

        PVSCVRNKGICVPIRCPGNMKQIGTC
    

Molecular Weight2774.38 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)3.92

Net Charge (pH 7.4) 3.80

Charge Density (pH 7.0) 0.1507

GRAVY Index0.12

Hydrophobic Moment 0.47

Boman Index0.01

Instability Index48.46

Aliphatic Index 78.46

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1104.82

LogP -13.40

H-bond Donors 42.0

H-bond Acceptors 41.0

Rotatable Bonds 90.0

Heavy Atoms 189.0

Ring Count 3.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0067305 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)