Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length228 amino acids

Chemical FormulaC1163H1767N261O348S8

DescriptionStandard

        IDDLAEIDYSLNSLPAVFRPFIDLDLKGIVYPAGNYSDPPYVATPFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITVAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPIISLEQDSFTVEIQGSMEVFAVLPDSTTQSLFTMNIAANTSIALNIFDQKLMGSLCLNRLQFSLAHSNVGFFEISLLENILSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight25229.53 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-16.14

Net Charge (pH 7.4) -16.48

Charge Density (pH 7.0) -0.0708

GRAVY Index0.33

Hydrophobic Moment 0.60

Boman Index0.26

Instability Index48.43

Aliphatic Index 100.13

Aromaticity 0.1316

Extinction Coeff. Reduced 17880.00

Extinction Coeff. Oxidized 18005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0038316 VERIFIED: NO

Provenance & Taxonomy

OrganismCariama cristata [other]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria