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MYP_073894
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Basic Information
NF 5
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
21 amino acids
C104H184N26O24
Standard
Sequence
AGYLLGKINLKALAALAKKIL
Physicochemical Analysis
2182.73 Da
10.18
3.79
3.60
0.1805
0.93
0.58
0.32
-1.52
172.38
0.0476
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
812.72
-2.83
28.0
28.0
77.0
154.0
1.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0388236 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Transportan/TP10
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Biotinylation
None
N-term detail: Biotinylated at amino group of Lys
Bio-Activity Profile
Cell-penetrating peptide
Human bowes melanoma cells
Cellular uptake assay
PMID10930519 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10930519/
RECORD: Rec_0388979 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Transportan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PaperDesigned cell penetrating peptide dendrimers efficiently internalize cargo into cells PMID24870379 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24870379/
RECORD: Rec_0394665 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Transportan
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Stearylation
Amidation
α-NH2 group of Lys7 for subsequent synthesis
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID23357356 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23357356/
RECORD: Rec_0395230 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
TP10
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Cell-penetrating peptide Antiparasitic Antimalarial
Plasmodium falciparum HB3
30 μM
PLDH assay
PMID18519720 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18519720/
RECORD: Rec_0418144 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium tuberculosis H37Rv (ATCC 27294)
80 μM
MIC
PMID28314993 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28314993/
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