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MYP_073894
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Basic Information
NF 5
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
21 amino acids
C104H184N26O24
Standard
Sequence
AGYLLGKINLKALAALAKKIL
Physicochemical Analysis
2182.73 Da
10.18
3.79
3.60
0.1805
0.93
0.58
0.32
-1.52
172.38
0.0476
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
812.72
-2.83
28.0
28.0
77.0
154.0
1.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0251912 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperPatent US 2010/0279918 A1 Evidence URLhttps://patents.google.com/patent/US20100279918A1/en PatentUS 2010/0279918 A1
RECORD: Rec_0281541 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Transportan/TP10
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorophore labeling
None
N-term detail: Rhodamine-labelled
Bio-Activity Profile
Cell-penetrating peptide
CHO K1; HeLa; A549 cells
Fluorescence-based uptake assay
PMID15937518 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15937518/
RECORD: Rec_0283024 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Transportan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Rhodamine conjugation
None
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID15937518 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15937518/
RECORD: Rec_0293250 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic designed peptide
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
Bio-Activity Profile
Antimicrobial Antimycobacterial Anticancer
Mycobacterium smegmatis
6 μM
MIC
PMID14656995 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14656995/
RECORD: Rec_0297023 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Transportan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Stearylation
Conjugation with FAM to ε-NH2 group of additional lysine
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID25135660 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25135660/
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