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MYP_073894
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Basic Information
NF 5
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
21 amino acids
C104H184N26O24
Standard
Sequence
AGYLLGKINLKALAALAKKIL
Physicochemical Analysis
2182.73 Da
10.18
3.79
3.60
0.1805
0.93
0.58
0.32
-1.52
172.38
0.0476
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
812.72
-2.83
28.0
28.0
77.0
154.0
1.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0051321 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Transportan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID25108152 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25108152/
RECORD: Rec_0096016 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-negative
Candida glabrata
32 μM
MIC50
PMID23689723;28556271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23689723/
RECORD: Rec_0103726 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-negative
Neisseria meningitidis
PMID23689723;28556271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23689723/
RECORD: Rec_0119636 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
TP10
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Cell-penetrating peptide Antiparasitic Antitrypanosomal
Trypanosoma brucei brucei 427
2.7 μM
IC50; Alamar Blue assay
PMID18519720 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18519720/
RECORD: Rec_0130431 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Transportan
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
Oregon Green 488 coupled to Lys7
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PaperTranslocation of cell-penetrating peptides across the plasma membrane is controlled by cholesterol and microenvironment created by membranous proteins PMID25016968 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25016968/
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