Peptide Database

Peptide NameDermaseptin-5.1TR

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC118H193N31O33S2

DescriptionStandard

        GLWSKIKEAAKTAGKAAMGFVNEMV
    

Molecular Weight2638.11 Da

Isoelectric Point (pI)9.53

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.0705

GRAVY Index0.10

Hydrophobic Moment 0.64

Boman Index0.16

Instability Index8.88

Aliphatic Index 74.40

Aromaticity 0.0800

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1039.74

LogP -8.60

H-bond Donors 36.0

H-bond Acceptors 37.0

Rotatable Bonds 91.0

Heavy Atoms 184.0

Ring Count 3.0

Amide Bonds 25.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0326572 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa tarsius [Animal]

FamilyDermaseptin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetPseudomonas aeruginosa

FIRST PREV 1 ... 3 4 5

Showing 1 records on this page Ã‚Â· Page 5 of 5