Peptide Database

Peptide NameS15

Function Ontology

Immunology ▸ Cytokine / receptor signaling modulation ▸ TLR inhibition

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC145H240N54O34S2

DescriptionStandard

        EMFTILEEYFMYRGLRRRRRRRRR
    

Molecular Weight3347.93 Da

Isoelectric Point (pI)11.83

Net Charge (pH 7.0)6.84

Net Charge (pH 7.4) 6.66

Charge Density (pH 7.0) 0.2850

GRAVY Index-1.57

Hydrophobic Moment 0.64

Boman Index-0.81

Instability Index229.43

Aliphatic Index 48.75

Aromaticity 0.1667

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1524.21

LogP -12.19

H-bond Donors 61.0

H-bond Acceptors 43.0

Rotatable Bonds 117.0

Heavy Atoms 235.0

Ring Count 4.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0018788 VERIFIED: YES

Provenance & Taxonomy

OrganismOrthopoxvirus vaccinia [Virus]

FamilyP13/A52R-derived

Tax ID10245.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory Anti-inflammatory TLR inhibitor

TargetCpG- or LPS-stimulated RAW264.7 macrophage assays