Peptide Database

Peptide NameLeptin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC716H1176N196O219S5

DescriptionStandard

        VPIQKVQDDTKTLIKTVITRINDISHTQSVSSKQKVTGLDFIPGLHPILTLSKMDQTLAVYQQILTSMPSRNVIQISNDLENLRDLLHVLAFSKSCHLPWASGLETLDRLGGVLEASGYSTEVVALSRLQRSLQDMLWQLDLSPGC
    

Molecular Weight16194.50 Da

Isoelectric Point (pI)6.45

Net Charge (pH 7.0)-0.92

Net Charge (pH 7.4) -1.39

Charge Density (pH 7.0) -0.0063

GRAVY Index-0.01

Hydrophobic Moment 0.76

Boman Index0.06

Instability Index46.49

Aliphatic Index 113.42

Aromaticity 0.0411

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6685.14

LogP -68.02

H-bond Donors 232.0

H-bond Acceptors 227.0

Rotatable Bonds 545.0

Heavy Atoms 1136.0

Ring Count 18.0

Amide Bonds 160.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0222303 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo pygmaeus [Animal]

FamilyLeptin

Tax ID9600

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic