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MYP_073830
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Basic Information
Galanin
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
30 amino acids
C139H210N42O43
Standard
Sequence
GWTLNSAGYLLGPHAVGNHRSFSDKNGLTS
Physicochemical Analysis
3157.41 Da
8.60
0.93
0.63
0.0311
-0.45
0.31
0.08
7.09
68.33
0.1000
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1367.68
-17.93
48.0
46.0
99.0
224.0
7.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0224079 VERIFIED: YES
Provenance & Taxonomy
Ciona intestinalis [Animal]
Galanin
7719
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide Neuromodulator
PaperPeptidomic analysis of the central nervous system of the protochordate, Ciona intestinalis: homologs and prototypes of vertebrate peptides and novel peptides PMID21467196 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21467196/
RECORD: Rec_0229660 VERIFIED: YES
Provenance & Taxonomy
Ciona intestinalis [Animal]
Galanin
7719
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Experimental: 3.7±0.4 minutes; /222 seconds; Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Galanin (Ciona intestinalis): PMID 21467196##7689499 PMID21467196;7689499 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21467196/
RECORD: Rec_0265415 VERIFIED: YES
Provenance & Taxonomy
Bioactive neuropeptide Galanin [other]
Protein-derived CPP
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Biotinylation
None
N-term detail: Biotinyl-Gly-Gly-N 25galanin(1-29)
Bio-Activity Profile
Cell-penetrating peptide
Human bowes melanoma cells
Cellular uptake assay
PMID10930519 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10930519/
RECORD: Rec_0282023 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Endocrine
Radioimmunoassay
Human serum, in vivo; 222 s
PMID7689499 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7689499/
RECORD: Rec_0286786 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Galanin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide Neuromodulator
PMID1722333 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1722333/
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