Peptide Database

Peptide Namecycloviolacin H3

Function Ontology

Antiparasitic ▸ Anthelminthic

Antiparasitic ▸ Anthelminthic ▸ Nematicidal activity

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC126H193N35O40S5

DescriptionStandard

        GLPVGETCFGGTCNTPGCLCDPWPVCTRN
    

Molecular Weight2998.42 Da

Isoelectric Point (pI)4.37

Net Charge (pH 7.0)-1.29

Net Charge (pH 7.4) -1.56

Charge Density (pH 7.0) -0.0443

GRAVY Index0.02

Hydrophobic Moment 0.42

Boman Index0.16

Instability Index50.24

Aliphatic Index 46.90

Aromaticity 0.0690

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1162.35

LogP -14.95

H-bond Donors 43.0

H-bond Acceptors 44.0

Rotatable Bonds 85.0

Heavy Atoms 206.0

Ring Count 7.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0260408 VERIFIED: YES

Provenance & Taxonomy

OrganismViola odorata [Plant]

FamilyCyclotide

Tax ID97441

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Nematocidal Anthelmintic

TargetHaemonchus contortus

Activity0.85

MethodIC50

RECORD: Rec_0355544 VERIFIED: YES