Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length216 amino acids

Chemical FormulaC911H1429N267O298S4

DescriptionStandard

        MSGGDGRDHNSGAHNTGGNINGGPTGLGGNGGASDGSGWSSENNPWGGGSGSGVHWGGGSGNGNGGGNGNSGGGSNSSVAAVAFGFPALATPGAGTLGIAVSGEALSAAIADIFAALKGPFKFSAWGIALYGILPSEIAKDDPNMMSKIVTSLPAETVTNVQVSTLPLDQATVSVTKRVTDVVKDTRQHIAVVAGVPMSVPVVNAKPTRTPGVFHA
    

Molecular Weight21017.96 Da

Isoelectric Point (pI)6.16

Net Charge (pH 7.0)-2.05

Net Charge (pH 7.4) -2.54

Charge Density (pH 7.0) -0.0095

GRAVY Index-0.04

Hydrophobic Moment 0.69

Boman Index0.19

Instability Index28.19

Aliphatic Index 72.27

Aromaticity 0.0509

Extinction Coeff. Reduced 23490.00

Extinction Coeff. Oxidized 23490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0240378 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)