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MYP_073792
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Basic Information
Dermaseptin DRS-CA-1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
28 amino acids
C135H230N38O38S
Standard
Sequence
ALWKDLLKNVGKAAGKAVLNKVTDMVNQ
Physicochemical Analysis
3025.57 Da
9.83
2.79
2.60
0.0998
-0.06
0.71
0.03
5.67
111.43
0.0357
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1262.10
-11.02
42.0
42.0
106.0
212.0
2.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006476 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa camba [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus NCTC 10788
4 μM
MIC
PMID30258724 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30258724/
RECORD: Rec_0020340 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Phyllomedusa camba [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Klebsiella pneumoniae
8 μM
MIC
PaperDiscovery of two skin-derived dermaseptins and design of a TAT-fusion analogue with broad-spectrum antimicrobial activity and low cytotoxicity on healthy cells.
RECORD: Rec_0122850 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Phyllomedusa camba [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Enterococcus faecalis
128 μM
MIC
PaperDiscovery of two skin-derived dermaseptins and design of a TAT-fusion analogue with broad-spectrum antimicrobial activity and low cytotoxicity on healthy cells.
RECORD: Rec_0155133 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Phyllomedusa camba [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Staphylococcus aureus MRSA
4-8 μM
MIC
PaperDiscovery of two skin-derived dermaseptins and design of a TAT-fusion analogue with broad-spectrum antimicrobial activity and low cytotoxicity on healthy cells.
RECORD: Rec_0169299 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Phyllomedusa camba [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Pseudomonas aeruginosa
8 μM
MIC
PaperDiscovery of two skin-derived dermaseptins and design of a TAT-fusion analogue with broad-spectrum antimicrobial activity and low cytotoxicity on healthy cells.
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