Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length112 amino acids

Chemical FormulaC550H850N160O159S9

DescriptionStandard

        MERLFWPQALLLVALLFPGLCGTRHVSQGGTEGPRAPRDEAFRPGTNDSHSLHHPGKRYLVPLTPLLADYGTGFKVVNCRKSEGHCQEYCNYMEVQVGYCSERKDACCLPQN
    

Molecular Weight12536.19 Da

Isoelectric Point (pI)7.62

Net Charge (pH 7.0)0.88

Net Charge (pH 7.4) 0.28

Charge Density (pH 7.0) 0.0079

GRAVY Index-0.44

Hydrophobic Moment 0.60

Boman Index-0.04

Instability Index32.66

Aliphatic Index 68.75

Aromaticity 0.0893

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5074.34

LogP -51.43

H-bond Donors 180.0

H-bond Acceptors 174.0

Rotatable Bonds 400.0

Heavy Atoms 878.0

Ring Count 25.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0226065 VERIFIED: NO

Provenance & Taxonomy

OrganismMyotis lucifugus [Animal]

Tax ID59463

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence