Peptide Database

Peptide NameBeta-defensin 4 (BNBD-4) (BNDB-4)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length63 amino acids

Chemical FormulaC314H512N100O74S9

DescriptionStandard

        MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR
    

Molecular Weight7160.63 Da

Isoelectric Point (pI)11.46

Net Charge (pH 7.0)8.62

Net Charge (pH 7.4) 8.21

Charge Density (pH 7.0) 0.1367

GRAVY Index0.35

Hydrophobic Moment 0.58

Boman Index0.05

Instability Index46.73

Aliphatic Index 92.70

Aromaticity 0.0794

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2779.21

LogP -25.17

H-bond Donors 106.0

H-bond Acceptors 94.0

Rotatable Bonds 230.0

Heavy Atoms 497.0

Ring Count 12.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0087975 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyBeta-defensin; Defensin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0188609 VERIFIED: YES