Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length106 amino acids

Chemical FormulaC520H821N155O162S12

DescriptionStandard

        RLKLEKMYSKTNTSSTIFEKITNSSCSCLLSARSEGHHIIFNRWKACIAIGGRCKNQCDDSELRISYCERPTTHCCMRKCDPMDPNNWIPKDSVGTQEWYPKDSSH
    

Molecular Weight12220.80 Da

Isoelectric Point (pI)8.61

Net Charge (pH 7.0)4.03

Net Charge (pH 7.4) 3.46

Charge Density (pH 7.0) 0.0380

GRAVY Index-0.78

Hydrophobic Moment 0.45

Boman Index-0.19

Instability Index56.18

Aliphatic Index 53.40

Aromaticity 0.0755

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5162.05

LogP -60.94

H-bond Donors 191.0

H-bond Acceptors 182.0

Rotatable Bonds 407.0

Heavy Atoms 849.0

Ring Count 20.0

Amide Bonds 113.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0276487 VERIFIED: NO

Provenance & Taxonomy

OrganismRhinopithecus roxellana [Animal]

FamilyDefensin

Tax ID61622

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence