Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC378H600N92O102S10

DescriptionStandard

        MEKKSLPGLCFLFLVLFLTQEESVVIGAKVCQVPSRTFTGVCVPLDFPFCDSDCKKKEHAIKGKCVAFSCYCIKGC
    

Molecular Weight8386.01 Da

Isoelectric Point (pI)8.40

Net Charge (pH 7.0)2.50

Net Charge (pH 7.4) 2.08

Charge Density (pH 7.0) 0.0329

GRAVY Index0.43

Hydrophobic Moment 0.57

Boman Index0.16

Instability Index32.07

Aliphatic Index 85.79

Aromaticity 0.1053

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3064.77

LogP -23.61

H-bond Donors 113.0

H-bond Acceptors 116.0

Rotatable Bonds 277.0

Heavy Atoms 582.0

Ring Count 13.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0049910 VERIFIED: NO

Provenance & Taxonomy

OrganismMedicago truncatula [Plant]

Tax ID3880

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence