Peptide Database

Peptide NameGranulin-5

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length54 amino acids

Chemical FormulaC225H343N65O83S12

DescriptionStandard

        VPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCVAEGQCQ
    

Molecular Weight5671.30 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-6.20

Net Charge (pH 7.4) -6.70

Charge Density (pH 7.0) -0.1148

GRAVY Index-0.16

Hydrophobic Moment 0.31

Boman Index0.06

Instability Index31.63

Aliphatic Index 39.63

Aromaticity 0.0370

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2319.46

LogP -35.02

H-bond Donors 87.0

H-bond Acceptors 91.0

Rotatable Bonds 171.0

Heavy Atoms 385.0

Ring Count 10.0

Amide Bonds 59.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0342811 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Familygranulin family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3-15; 9-25; 34-47; 41-53

Bio-Activity Profile

Function

Cytokine Growth factor granulin family Growth factor signaling