Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC414H656N118O126S15

DescriptionStandard

        MKTFRVTVAVAVMLTFICIQESSAGPVSEVQELEEPMNNDNPVVVHEEMSEESWKMPYNRQKRNPAGCRFCCGCCPNMRGCGVCCKF
    

Molecular Weight9783.33 Da

Isoelectric Point (pI)5.77

Net Charge (pH 7.0)-1.48

Net Charge (pH 7.4) -1.90

Charge Density (pH 7.0) -0.0170

GRAVY Index-0.19

Hydrophobic Moment 0.44

Boman Index-0.02

Instability Index67.41

Aliphatic Index 55.86

Aromaticity 0.0690

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3914.11

LogP -42.15

H-bond Donors 140.0

H-bond Acceptors 141.0

Rotatable Bonds 320.0

Heavy Atoms 673.0

Ring Count 14.0

Amide Bonds 95.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0376868 VERIFIED: NO

Provenance & Taxonomy

OrganismChlorophthalmus bicornis [Animal]

FamilyHepcidin

Tax ID1225554

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal