Peptide Database

Peptide NameCoumarin-modified GLP-1 derivative 7

Function Ontology

Binding / Molecular interaction ▸ Binding activity

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC146H220N38O44

DescriptionStandard

        HAEGTFTSDVSYLEGQAAKEFIAWLVKGR
    

Molecular Weight3211.54 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-1.15

Net Charge (pH 7.4) -1.41

Charge Density (pH 7.0) -0.0395

GRAVY Index-0.21

Hydrophobic Moment 0.48

Boman Index0.09

Instability Index11.32

Aliphatic Index 74.14

Aromaticity 0.1379

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1329.97

LogP -11.88

H-bond Donors 47.0

H-bond Acceptors 44.0

Rotatable Bonds 105.0

Heavy Atoms 228.0

Ring Count 6.0

Amide Bonds 29.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0120406 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGLP-1

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermNone

C-TermAmidation

Other ModsX-2 = Cys- conjugated-7-hydroxyCoumarin maleimide

Bio-Activity Profile

Function

Receptor-binding

MethodEC50

Half-LifeRat Plasma, in vivo; 82440 s