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MYP_073533
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Basic Information
OH-CATH (Snakes, reptiles, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
34 amino acids
C202H334N56O38
Standard
Sequence
KRFKKFFKKLKNSVKKRAKKFFKKPRVIGVSIPF
Physicochemical Analysis
4155.17 Da
12.00
14.75
14.53
0.4338
-0.74
0.81
-0.33
10.16
62.94
0.1765
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1587.53
-8.18
57.0
53.0
150.0
296.0
8.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0085304 VERIFIED: YES
Provenance & Taxonomy
Ophiophagus hannah [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
16 μg/mL
MIC
PMID25100358 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25100358/
RECORD: Rec_0086870 VERIFIED: YES
Provenance & Taxonomy
Ophiophagus hannah [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa clinic strain
2 μg/mL
MIC
PaperIdentification and characterization of novel reptile cathelicidins from elapid snakes. Peptides. 2008 Oct;29(10):1685-1691. doi: 10.1016/j.peptides.2008.06.008. PMID: 18620012. PMID18620012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18620012/
RECORD: Rec_0110774 VERIFIED: YES
Provenance & Taxonomy
Ophiophagus hannah [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae
8 μg/mL
MIC
PMID25100358 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25100358/
RECORD: Rec_0121195 VERIFIED: YES
Provenance & Taxonomy
Ophiophagus hannah [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli ML-35P
6 μg/mL
MIC
PaperIdentification and characterization of novel reptile cathelicidins from elapid snakes. Peptides. 2008 Oct;29(10):1685-1691. doi: 10.1016/j.peptides.2008.06.008. PMID: 18620012. PMID18620012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18620012/
RECORD: Rec_0148037 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Ophiophagus hannah [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial
Escherichia coli
6-20 μg/mL
MIC
PaperIdentification and characterization of novel reptile cathelicidins from elapid snakes.
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