‹ ›
MYP_073533
← PREVIOUS NEXT → BACK
Basic Information
OH-CATH (Snakes, reptiles, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
34 amino acids
C202H334N56O38
Standard
Sequence
KRFKKFFKKLKNSVKKRAKKFFKKPRVIGVSIPF
Physicochemical Analysis
4155.17 Da
12.00
14.75
14.53
0.4338
-0.74
0.81
-0.33
10.16
62.94
0.1765
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1587.53
-8.18
57.0
53.0
150.0
296.0
8.0
34.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0018955 VERIFIED: YES
Provenance & Taxonomy
Ophiophagus hannah [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
4 μg/mL
MIC
PaperIdentification and characterization of novel reptile cathelicidins from elapid snakes. Peptides. 2008 Oct;29(10):1685-1691. doi: 10.1016/j.peptides.2008.06.008. PMID: 18620012. PMID18620012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18620012/
RECORD: Rec_0033027 VERIFIED: YES
Provenance & Taxonomy
Ophiophagus hannah [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus pyogenes
16 μg/mL
MIC
PMID25100358 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25100358/
RECORD: Rec_0044733 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0051581 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Ophiophagus hannah [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa
6.25-12.5 μg/mL
MIC
PaperIdentification and characterization of novel reptile cathelicidins from elapid snakes.
RECORD: Rec_0066569 VERIFIED: YES
Provenance & Taxonomy
Ophiophagus hannah [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Enterobacter aerogenes clinic strain
2 μg/mL
MIC
PaperIdentification and characterization of novel reptile cathelicidins from elapid snakes. Peptides. 2008 Oct;29(10):1685-1691. doi: 10.1016/j.peptides.2008.06.008. PMID: 18620012. PMID18620012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18620012/
1 2 3 ... 7 NEXT LAST
Showing 5 records on this page · Page 1 of 7