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MYP_073520
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiparasitic ▸ Anthelminthic
Antiparasitic ▸ Anthelminthic ▸ Nematicidal activity
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
30 amino acids
C131H214N36O39S6
Standard
Sequence
GIPCGESCVFIPCITGAIGCSCKSKVCYRN
Physicochemical Analysis
3109.71 Da
8.33
1.70
1.40
0.0567
0.58
0.30
0.20
13.00
74.67
0.0667
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1185.12
-14.10
47.0
47.0
98.0
212.0
4.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0243504 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0245820 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea [Plant]
Clitoria ternatea
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial
PMID21596752;18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21596752/
RECORD: Rec_0249356 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
4-20, 8-22, 13-27
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer
PMID21596752 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21596752/
RECORD: Rec_0257581 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide; DSSP H 10.0%, E 6.7%, T 43.3%, C 40.0% [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Antibacterial Toxic Antimicrobial Anti-Gram-positive Cytotoxic Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0268123 VERIFIED: NO
Provenance & Taxonomy
Butterfly pea [Plant]; Fabaceae [Plant]
Cyclotide
33090; 3803
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
4-20; 8-22; 13-27
Bio-Activity Profile
Antimicrobial
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