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MYP_073500
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
16 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
GFXGKXGFXGKXKKKK
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0084938 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
residue-level stereochemical modification [Mixed]
Acetylation
Amidation
Tic= tetrahydroisoquinolinecarboxylic acid
Bio-Activity Profile
Toxic Hemolytic Antibiotic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0099805 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Tic= tetrahydroisoquinolinecarboxylic acid
Bio-Activity Profile
Antimicrobial Antibiotic
Mouse erythrocytes
25 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/17547385/ PMID17547385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17547385/
RECORD: Rec_0257125 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
tetrahydroisoquinolinecarboxylic acid, C terminal -CONH2, N terminal -acetyl at 3,6,9,12; tetrahydroisoquinolinecarboxylic acid, C terminal -CONH2, N terminal -acetyl
Bio-Activity Profile
Antimicrobial Antibacterial
MIC against Salmonella typhimurium
PMID17547385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17547385/
RECORD: Rec_0344307 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
tetrahydroisoquinolinecarboxylic acid, C terminal -CONH2, N terminal -acetyl at 3,6,9,12; tetrahydroisoquinolinecarboxylic acid, C terminal -CONH2, N terminal -acetyl
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtillis
PMID17547385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17547385/
RECORD: Rec_0379652 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
tetrahydroisoquinolinecarboxylic acid, C terminal -CONH2, N terminal -acetyl at 3,6,9,12; tetrahydroisoquinolinecarboxylic acid, C terminal -CONH2, N terminal -acetyl
Bio-Activity Profile
Antimicrobial Antibacterial
Mycobacterium ranae
PMID17547385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17547385/
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