Peptide Database

Peptide NameHepcidin1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length85 amino acids

Chemical FormulaC404H648N108O124S12

DescriptionStandard

        MKIFSVAVAVAVVLTFICIQESSAVPVAEELELEVPMIPDTPDAHGETSVDSWEMLYKSRQKRDDRCRLCCGCCEPGICGVCCRF
    

Molecular Weight9386.90 Da

Isoelectric Point (pI)4.67

Net Charge (pH 7.0)-5.48

Net Charge (pH 7.4) -5.90

Charge Density (pH 7.0) -0.0644

GRAVY Index0.26

Hydrophobic Moment 0.38

Boman Index0.09

Instability Index29.14

Aliphatic Index 87.06

Aromaticity 0.0588

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3669.18

LogP -34.07

H-bond Donors 135.0

H-bond Acceptors 132.0

Rotatable Bonds 305.0

Heavy Atoms 648.0

Ring Count 12.0

Amide Bonds 86.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0201081 VERIFIED: NO

Provenance & Taxonomy

OrganismChelon ramada [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal