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MYP_073457
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Basic Information
Nigrocin-AA1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Standard
21 amino acids
C86H155N25O24S2
Standard
Sequence
GLLSGILGAGKRIVCGLSGLC
Physicochemical Analysis
1987.43 Da
8.96
1.74
1.51
0.0828
1.27
0.55
0.42
18.05
148.57
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
773.70
-7.88
30.0
28.0
68.0
137.0
0.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0114583 VERIFIED: YES
Provenance & Taxonomy
Amolops afghanus [Animal]
Nigrocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
15-21
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli ATCC 25922 or IS37# or IS117# or IS218#
5-20 μg/mL
MIC
PaperNovel peptides from skins of amphibians showed broad-spectrum antimicrobial activities. PMID26452973
RECORD: Rec_0117620 VERIFIED: YES
Provenance & Taxonomy
Amolops afghanus [Animal]
Nigrocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
15-21
Bio-Activity Profile
Antimicrobial Antifungal
Enterococcus faecalis ATCC 29212
10 μg/mL
MIC
PaperNovel peptides from skins of amphibians showed broad-spectrum antimicrobial activities. PMID26452973
RECORD: Rec_0119418 VERIFIED: YES
Provenance & Taxonomy
Amolops afghanus [Animal]
Nigrocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 25922
5 μg/mL
MIC
PMID26452973 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26452973/
RECORD: Rec_0119457 VERIFIED: YES
Provenance & Taxonomy
Amolops afghanus [Animal]
Nigrocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae IS59#
20 μg/mL
MIC
PMID26452973 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26452973/
RECORD: Rec_0162142 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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