Peptide Database

Peptide NameHeat-stable enterotoxin II

Function Ontology

CGMP Activator

Standard StatusStandard

Sequence Length48 amino acids

Chemical FormulaC216H354N66O67S5

DescriptionStandard

        STQSNKKDLCEHYRQIAKESCKKGFLGVRDGTAGACFGAQIMVAAKGC
    

Molecular Weight5107.85 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)3.51

Net Charge (pH 7.4) 3.18

Charge Density (pH 7.0) 0.0731

GRAVY Index-0.37

Hydrophobic Moment 0.66

Boman Index-0.08

Instability Index41.50

Aliphatic Index 57.08

Aromaticity 0.0625

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2182.56

LogP -27.15

H-bond Donors 80.0

H-bond Acceptors 77.0

Rotatable Bonds 178.0

Heavy Atoms 354.0

Ring Count 4.0

Amide Bonds 51.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0049193 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

Tax ID562

Structure & Mods

Configlinear disulfide-stabilized peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide10-48, 21-36

Bio-Activity Profile

Function

CGMP Activator