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MYP_073395
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Basic Information
gH626-644(derived from HSV-1 H glycoprotein)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C100H153N29O25
Standard
Sequence
GLASTLTRWAHYNALIRAF
Physicochemical Analysis
2161.46 Da
10.84
1.85
1.59
0.0972
0.28
0.53
0.17
50.37
103.16
0.1579
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
879.40
-6.94
33.0
28.0
66.0
154.0
5.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0340878 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HSV Entry inhibition
Herpes simplex virus type 1(HSV-1) | Vero cells
250 μM
% inhibition
Mammalian: 30 h; Yeast: >20 h; E. coli: >10 h
PaperPeptides containing membrane-interacting motifs inhibit herpes simplex virus type 1 infectivity. | Galdiero S, Falanga A, Vitiello M, D'Isanto M, Cantisani M, Kampanaraki A, Benedetti E, Browne H, Galdiero M. | Peptides. 2008 Sep;29(9):1461-71. | DOI:10.1016/j.peptides.2008.04.022 | PMID:18572274 PMID18572274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18572274/
RECORD: Rec_0421747 VERIFIED: YES
Provenance & Taxonomy
Human alphaherpesvirus 1 [Virus]
Virus-derived peptide
10298;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
Herpes simplex virus 1 (Virus entry); Vero
250 μM
Plaque assay
PaperPeptides containing membrane-interacting motifs inhibit herpes simplex virus type 1 infectivity. | Galdiero S, Falanga A, Vitiello M, D'Isanto M, Cantisani M, Kampanaraki A, Benedetti E, Browne H, Galdiero M. | Peptides. 2008 | PMID:18572274 PMID18572274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18572274/
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