Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length83 amino acids

Chemical FormulaC435H681N123O115S10

DescriptionStandard

        MKFLFLFLVIPLAMDPVLSGRHHTLRCMGNVGVCRPSCRKTEQPYLYCLNYQPCCLQSYMRISISGREEKNDWSQQNRWPKIP
    

Molecular Weight9794.47 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)5.62

Net Charge (pH 7.4) 5.20

Charge Density (pH 7.0) 0.0677

GRAVY Index-0.32

Hydrophobic Moment 0.53

Boman Index-0.05

Instability Index66.76

Aliphatic Index 76.27

Aromaticity 0.1084

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3831.38

LogP -32.60

H-bond Donors 138.0

H-bond Acceptors 133.0

Rotatable Bonds 316.0

Heavy Atoms 683.0

Ring Count 20.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0390972 VERIFIED: NO

Provenance & Taxonomy

OrganismCallorhinus ursinus [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence