Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC331H548N92O99S10

DescriptionStandard

        MKLSLRLVSVFLLSFMLLLASGKGPVEARTCESVSGKFSGVCLNSANCAKICPTEGFSSGRCSSLRCYCSKSC
    

Molecular Weight7721.10 Da

Isoelectric Point (pI)9.08

Net Charge (pH 7.0)5.42

Net Charge (pH 7.4) 5.08

Charge Density (pH 7.0) 0.0743

GRAVY Index0.43

Hydrophobic Moment 0.52

Boman Index0.10

Instability Index31.86

Aliphatic Index 84.11

Aromaticity 0.0685

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3060.63

LogP -37.47

H-bond Donors 119.0

H-bond Acceptors 115.0

Rotatable Bonds 259.0

Heavy Atoms 532.0

Ring Count 7.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0165364 VERIFIED: NO

Provenance & Taxonomy

OrganismArabis alpina [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence