Peptide Database

Peptide NamePreprocathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length159 amino acids

Chemical FormulaC784H1274N218O232S5

DescriptionStandard

        METQRASLSLGRWSLWLLLLGLALPSASAQALSYREAVLRAVDQLNEKSSEANLYRLLELDPPPKEDDENPNIPKPVSFRVKETVCPRTSQQPPEQCDFKENGLLKECVGTVTLDQVGSNFDITCAVPQSVGGLRSLGRKILRAWKKYGPIIVPIIRIG
    

Molecular Weight17626.15 Da

Isoelectric Point (pI)8.37

Net Charge (pH 7.0)1.49

Net Charge (pH 7.4) 1.17

Charge Density (pH 7.0) 0.0094

GRAVY Index-0.24

Hydrophobic Moment 0.95

Boman Index-0.02

Instability Index41.58

Aliphatic Index 99.94

Aromaticity 0.0566

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21220.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7229.02

LogP -69.64

H-bond Donors 250.0

H-bond Acceptors 239.0

Rotatable Bonds 582.0

Heavy Atoms 1239.0

Ring Count 25.0

Amide Bonds 172.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0141284 VERIFIED: NO

Provenance & Taxonomy

OrganismBos mutus [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal