Peptide Database

Peptide NameAbatacept

Function Ontology

Anticancer

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Immunomodulation ▸ Immuno-oncology

Standard StatusStandard

Sequence Length357 amino acids

Chemical FormulaC1749H2729N461O545S16

DescriptionStandard

        MHVAQPAVVLASSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYLGIGNGTQIYVIDPEPCPDSDQEPKSSDKTHTSPPSPAPELLGGSSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
    

Molecular Weight39447.18 Da

Isoelectric Point (pI)5.67

Net Charge (pH 7.0)-6.85

Net Charge (pH 7.4) -7.71

Charge Density (pH 7.0) -0.0192

GRAVY Index-0.40

Hydrophobic Moment 0.55

Boman Index0.01

Instability Index47.37

Aliphatic Index 74.71

Aromaticity 0.0812

Extinction Coeff. Reduced 45840.00

Extinction Coeff. Oxidized 46340.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0084537 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Cricetulus griseus [Animal]

FamilyMonoclonal antibody

Tax ID9606;10029

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsGlycosylation

Bio-Activity Profile

Function

Anticancer Immunomodulatory Immuno-oncology

TargetCHO

Half-Life16.7 (12-23) days in healthy subjects

RECORD: Rec_0175849 VERIFIED: NO