Peptide Database

Peptide NameTemporin-ALf (Amolopin-2g)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC329H536N88O97S2

DescriptionStandard

        MFTLKKSLLLLFFLGTINLSLCEQERNAEEERRDEPDERNAEVEKRFFPIVGKLLSGLSGLLGK
    

Molecular Weight7340.44 Da

Isoelectric Point (pI)5.39

Net Charge (pH 7.0)-1.49

Net Charge (pH 7.4) -1.74

Charge Density (pH 7.0) -0.0232

GRAVY Index-0.24

Hydrophobic Moment 0.69

Boman Index-0.05

Instability Index39.50

Aliphatic Index 103.59

Aromaticity 0.0781

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3022.68

LogP -24.63

H-bond Donors 105.0

H-bond Acceptors 98.0

Rotatable Bonds 257.0

Heavy Atoms 516.0

Ring Count 7.0

Amide Bonds 67.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0165443 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops loloensis [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0306232 VERIFIED: YES