Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length180 amino acids

Chemical FormulaC888H1402N246O237S11

DescriptionStandard

        HEPMLLLAVSEFMANSAAFTYFMAGALRRNISNNMLPRRFPLQLTTKSMGVFSPQLQEHSPAHPMELHLSARRQPLLSCHPNALHGALFSSAEAFVVLPNATRVPAFVLNIDANVTGKPTFTGNRLQGTVSLTGPLCLPHAGLRGLLVLQVKRLETLLKFGLWLFGVPWANSECCSCPVP
    

Molecular Weight19668.85 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)6.34

Net Charge (pH 7.4) 5.69

Charge Density (pH 7.0) 0.0352

GRAVY Index0.21

Hydrophobic Moment 0.54

Boman Index0.16

Instability Index64.24

Aliphatic Index 95.94

Aromaticity 0.0778

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7560.36

LogP -82.94

H-bond Donors 261.0

H-bond Acceptors 261.0

Rotatable Bonds 622.0

Heavy Atoms 1382.0

Ring Count 39.0

Amide Bonds 195.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0125073 VERIFIED: NO

Provenance & Taxonomy

OrganismHeliornis fulica [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria