Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC570H899N149O171S4

DescriptionStandard

        PDLSGYEKYRLGNVKYNISRIHVTAVEFPSASMSFIPGSGIKLVIANASLTIDMNWNIRTWIFKDSGRSTVYISKVFVTAIFSTPLDNMDYKSISLTSCRTSSGEISIKPNEKN
    

Molecular Weight12703.39 Da

Isoelectric Point (pI)9.35

Net Charge (pH 7.0)4.04

Net Charge (pH 7.4) 3.89

Charge Density (pH 7.0) 0.0354

GRAVY Index-0.11

Hydrophobic Moment 0.53

Boman Index0.06

Instability Index24.95

Aliphatic Index 87.19

Aromaticity 0.1053

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5167.71

LogP -54.36

H-bond Donors 185.0

H-bond Acceptors 180.0

Rotatable Bonds 419.0

Heavy Atoms 894.0

Ring Count 20.0

Amide Bonds 121.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0107220 VERIFIED: NO

Provenance & Taxonomy

OrganismOreotrochilus melanogaster [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria