Peptide Database

Peptide NameLiver-expressed antimicrobial peptide 2 (LEAP-2)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC385H643N121O102S8

DescriptionStandard

        MWHLKLFAVLMICLLLLAQVDGSPIPQQSSAKRRPRRMTPFWRAVSLRPIGASCRDDSECITRLCRKRRCSLSVAQE
    

Molecular Weight8855.49 Da

Isoelectric Point (pI)10.73

Net Charge (pH 7.0)8.55

Net Charge (pH 7.4) 8.20

Charge Density (pH 7.0) 0.1110

GRAVY Index-0.09

Hydrophobic Moment 0.67

Boman Index-0.11

Instability Index84.63

Aliphatic Index 93.77

Aromaticity 0.0519

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3611.35

LogP -34.57

H-bond Donors 136.0

H-bond Acceptors 120.0

Rotatable Bonds 294.0

Heavy Atoms 616.0

Ring Count 12.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0127198 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyLEAP2

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Non-hemolytic