Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length112 amino acids

Chemical FormulaC532H882N132O148S2

DescriptionStandard

        MVNSLTNKKRVFLFVVIGLVLATLSSVAYISTLQITIHQTAVLPGNAYLASTLGISTAAAKKAIDIIDTASTIASIISLIGVVTGAGAISYAVVATAKAMIKKYGKKYAAAW
    

Molecular Weight11559.62 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)7.58

Net Charge (pH 7.4) 7.29

Charge Density (pH 7.0) 0.0676

GRAVY Index0.87

Hydrophobic Moment 0.60

Boman Index0.35

Instability Index17.11

Aliphatic Index 129.91

Aromaticity 0.0714

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 12950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4441.21

LogP -39.08

H-bond Donors 159.0

H-bond Acceptors 159.0

Rotatable Bonds 382.0

Heavy Atoms 814.0

Ring Count 11.0

Amide Bonds 116.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0419336 VERIFIED: NO

Provenance & Taxonomy

OrganismWeizmannia coagulans 36D1 [Bacterium]

FamilyBacteriocin

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal