Peptide Database

Peptide NameRegenerating islet-derived protein 3-gamma (REG-3-gamma) (Pancreatitis-associated protein 1B) (PAP-1B) (Pancreatitis-associated protein IB) (PAP IB) (Regenerating islet-derived protein III-gamma) (REG III) (Reg III-gamma) [Cleaved into: Regenerating islet-derived protein 3-gamma 16.5 kDa form; Regenerating islet-derived protein 3-gamma 15 kDa form]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Binding / Molecular interaction ▸ Carbohydrate-binding peptide ▸ Lectin

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length175 amino acids

Chemical FormulaC866H1324N220O256S13

DescriptionStandard

        MLPPMALPSVSWMLLSCLILLCQVQGEETQKELPSPRISCPKGSKAYGSPCYALFLSPKSWMDADLACQKRPSGKLVSVLSGAEGSFVSSLVRSISNSYSYIWIGLHDPTQGSEPDGDGWEWSSTDVMNYFAWEKNPSTILNPGHCGSLSRSTGFLKWKDYNCDAKLPYVCKFKD
    

Molecular Weight19329.94 Da

Isoelectric Point (pI)6.70

Net Charge (pH 7.0)-0.39

Net Charge (pH 7.4) -0.87

Charge Density (pH 7.0) -0.0022

GRAVY Index-0.22

Hydrophobic Moment 0.68

Boman Index0.08

Instability Index49.05

Aliphatic Index 73.54

Aromaticity 0.1086

Extinction Coeff. Reduced 48930.00

Extinction Coeff. Oxidized 49430.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7527.83

LogP -77.69

H-bond Donors 267.0

H-bond Acceptors 271.0

Rotatable Bonds 617.0

Heavy Atoms 1355.0

Ring Count 42.0

Amide Bonds 184.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0210516 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-MRSA Anti-Gram-positive Lectin Non-hemolytic

TargetListeria monocytogenes (Gram-positive)