Peptide Database

Peptide Namealdafermin

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length190 amino acids

Chemical FormulaC940H1476N266O279S11

DescriptionStandard

        MRDSSPLVHYGWGDPIRLRHLYTSGPHGLSSCFLRIRADGVVDCARGQSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEEDCAFEEEIRPDGYNVYRSEKHRLPVSLSSAKQRQLYKNRGFLPLSHFLPMLPMVPEEPEDLRGHLESDMFSSPLETDSMDPFGLVTGLEAVRSPSFEK
    

Molecular Weight21320.10 Da

Isoelectric Point (pI)6.24

Net Charge (pH 7.0)-2.80

Net Charge (pH 7.4) -3.54

Charge Density (pH 7.0) -0.0148

GRAVY Index-0.35

Hydrophobic Moment 0.50

Boman Index-0.03

Instability Index59.34

Aliphatic Index 81.05

Aromaticity 0.0789

Extinction Coeff. Reduced 15930.00

Extinction Coeff. Oxidized 16180.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8666.08

LogP -101.37

H-bond Donors 306.0

H-bond Acceptors 295.0

Rotatable Bonds 700.0

Heavy Atoms 1496.0

Ring Count 37.0

Amide Bonds 196.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0224838 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Immunomodulatory Signaling peptide

Targetfibroblast growth factor receptor 4 (Human)